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Antibiotic Prophylaxis


Antibiotic Prophylaxis or premedication before Dental treatment.




What do you mean by antibiotics? A medicine inhabits the growth or destroys microorganisms or bacterial infections. They do this by killing the bacteria or keeping them from copying themselves or producing. Have you ever wondered how antibiotics kill involving bacteria, while leaving human cells alone? Although there are comparations between bacteria and human cells, there are many differences as well. Antibiotics work by influencing things that bacterial cells have but human cells don’t. Human cells do not have cell walls, while many types of bacteria too.

Bacteria and human cells also differ in the structure of their cell membrane and machinery they use to build proteins or copy DNA some antibiotics dissolve the membrane of bacterial cells; others affect protein structure or DNA copying machinery that is specific to bacteria. Different families of antibiotics have a different way of killing bacteria. Beta-lactam antibiotics kill bacteria that are encircled by a cell wall. Some antibiotics used to treat infections like bronchitis (inflammation of the lining of bronchial tubes which carry air to and from the lungs) and pneumonia (inflammation of lungs). When bacteria begin to copy their DNA, quinolones cause the strands to break from being repaired, without intact DNA bacteria cannot live or reproduce.
Recommendations for antibiotics prophylaxis prior to certain dental procedures have existed historically for two groups of patients. Those with heart conditions that may predispose them to infective endocarditis (infection of an inner surface of the heart usually the valves). Those who have a knee joint replacement and may be at risk for developing hematogenous infections at the site of the knee joint. The national institute of dental and craniofacial research recommends that in patients receiving chemotherapy who have a central venous catheter, dental professionals consult the treating oncologist (cancer specialist) about the need for antibiotics prophylaxis before any dental procedure. The most common route of a bacterial infection in the body is through the skin, while normal tissue can typically defend itself against the involving bacteria, the inorganic material of prosthesis (artificial knee joint) cannot. It is there that an infection can seed and cause damage to adjacent bone and tissue.
There are also certain individuals who are inherently at risk of infection due to either a severely weakened or abnormal immune response. In many cases, these individuals are not only able to fight with infection but to control it once it occurs.


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